The treatment of autonomic dysfunction in tetanus
We report a case of generalised tetanus in a 50-year-old female patient after sustaining a wound to her right lower leg. She developed autonomic dysfunction, which included labile hypertension alternating with hypotension and sweating. The autonomic dysfunction was treated successfully with a combination of morphine sulphate infusion, magnesium sulphate, and clonidine. She also received adrenaline and phenylephrine infusions as needed for hypotension. We then discuss the pathophysiology, clinical features and treatment options of autonomic dysfunction.
T van den Heever, Department of Critical Care, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa
M G L Spruyt, Department of Critical Care, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa
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Date published: 2017-07-11
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